Pirates vs. Reds Prediction, Odds, Picks – August 7 Updated Aug. 7, 2025 6:00 p.m. ET sharefacebookxredditlink Data Skrive Oneil Cruz and the Pittsburgh Pirates meet Spencer Steer and the Cincinnati Reds on Thursday at 6:40 p.m. ET. The favored Pirates have -169 moneyline odds to win against the underdog Reds, who are listed at +141. Pittsburgh (-1.5) is the favorite on the run line. The total is 6.5 runs for this game (with -120 odds to hit the over and +100 odds on the under). Here is everything you need from a betting perspective on the Pirates-Reds game, regarding the run line, moneyline and total, plus expert picks.Keep up with MLB on FOX Sports.Reds vs. Cubs Highlights | MLB on FOX Check out the best moments between the Cincinnati Reds and the Chicago Cubs. ADVERTISEMENT Pirates vs. Reds Game Information & OddsWhen: Thursday, August 7, 2025 at 6:40 p.m. ETWhere: PNC Park in Pittsburgh, PennsylvaniaHow to watch on TV: MLB Network, SportsNet PT, and FDSOH Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Run Line Favorite Run Line Odds Underdog Run Line Odds Pirates -169 +141 6.5 -120 +100 -1.5 +132 -158 Pirates vs. Reds PredictionScore Prediction: Pirates 4, Reds 3Total Prediction: Over 6.5 runsWin Probabilities: Pirates 51%, Reds 49%Pirates vs. Reds Betting InsightsThis season, the Pirates have been favored 33 times and won 15, or 45.5%, of those games.Pittsburgh has entered three games this season favored by -169 or more and is 1-2 in those contests.The implied probability of a win from the Pirates, based on the moneyline, is 62.8%.The Reds have been underdogs in 61 games this season and have come away with the win 32 times (52.5%) in those contests.This year, Cincinnati has won six of 15 games when listed as at least +141 or worse on the moneyline.The Reds have an implied victory probability of 41.5% according to the moneyline set for this matchup.Pirates Recent Betting PerformanceThe Pirates have a 2-2 record over the four games they were favored on the moneyline in their last 10 matchups.Over their last 10 matchups — all had a set run total — the Pirates and their opponents combined to go over the total six times.The Pirates’ ATS record is 6-4-0 over their past 10 games. Pirates Recent Stats Stat Avg/Total Record 6-4 Runs Per Game 5.5 HR 12 ERA 5.25 K/9 8.5 Pirates Player InsightsCruz paces the Pirates with 18 home runs.In all of MLB, Cruz is 48th in home runs and 96th in RBI.Andrew McCutchen is hitting .249 with 16 doubles, 11 home runs and 41 walks.McCutchen ranks 129th in homers and 161st in RBI on the season.McCutchen carries a two-game streak with at least one hit into this contest. In his last five games he is hitting .286 with a double, a home run, three walks and five RBIs.Bryan Reynolds has put up a team-high 53 runs batted in.Isiah Kiner-Falefa has a club-high .270 batting average.Kiner-Falefa brings a two-game streak with at least one hit into this one. In his last five games he is hitting .350 with a double and four RBIs.Pirates Team Props Hits O/U Total Bases O/U HR O/U RBI O/U Spencer Horwitz 0.5 (-245) 1.5 (+125) – 0.5 (+245) Oneil Cruz 0.5 (-205) 1.5 (+120) – 0.5 (+145) Nick Gonzales 0.5 (-260) 1.5 (+125) – 0.5 (+190) Bryan Reynolds 0.5 (-255) 1.5 (+110) – 0.5 (+150) Tommy Pham – – – – Reds Recent Betting PerformanceIn six games as underdogs over the last 10 matchups, the Reds have a record of 3-3.The Reds and their opponents have combined to hit the over just once in their last 10 games with a total.The Reds have a record of 6-4-0 ATS over their last 10 games. Reds Recent Stats Stat Avg/Total Record 5-5 Runs Per Game 3.8 HR 8 ERA 3.80 K/9 9.7 Reds Player InsightsElly De La Cruz paces the Reds with 19 home runs and 73 runs batted in, while recording a team-high batting average of .279.Among all hitters in MLB, De La Cruz is 41st in home runs and 16th in RBI.TJ Friedl has 16 doubles, two triples, 10 home runs and 54 walks while batting .275.Friedl is currently 148th in homers and 171st in RBI in the major leagues.Steer is hitting .236 with 15 doubles, two triples, 13 home runs and 32 walks.Matt McLain has 12 doubles, 11 home runs and 41 walks while hitting .223.Reds Team Props Hits O/U Total Bases O/U HR O/U RBI O/U Tyler Stephenson – – – – Jake Fraley – – – – Brady Singer – – – – TJ Friedl 0.5 (-175) – – 0.5 (+280) Spencer Steer 0.5 (-145) – – 0.5 (+285) Giants vs. Pirates Highlights | MLB on FOX Check out the best moments between the Pittsburgh Pirates and the San Francisco Giants. FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.Want great stories delivered right to your inbox? Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily. FOLLOW Follow your favorites to personalize your FOX Sports experience Pittsburgh Pirates Cincinnati Reds What did you think of this story?